PHYS201 · Reading edition
Cardiac output and what sets it
Within limits, the heart pumps out whatever volume is returned to it. So on the graph you have end-diastolic volume along the x axis, stroke volume up the y axis, and the curve rises steeply at first and then flattens off at high volumes.
A little bit of history, because I like it. Otto Frank was a German physiologist working on frog hearts in the eighteen nineties, and Ernest Starling was in London about twenty years later with his heart-lung preparation in dogs. They never worked together.